Autism and the Broader Biological Gender Spectrum

I enjoy what Temple Grandin and John Elder Robison write with their direct method of communication in “pulling no punches” about the challenges and advantages of living on the spectrum.

I also found another person writing about living without a label on “a spectrum” and many things associated with it, equally, if not more impressive in what I can relate to as a spectrum.

What I write below, in a way, is a tribute to that person:

I enjoyed your article, and was having difficulty too, understanding what the “Neurotypical Privilege" comment meant, but it seems to be along the lines of the pejorative phrase "Uncle Tom", which I have seen thrown around in some places in online Autism Communities. Alternatively, Gay people staying in the closet, to gain what some might describe as "straight privilege"

http://www.thinkingautismguide.com/2013/04/weve-all-got-our-something.html

In the case of a Broader Autism Phenotype (BAP), it runs a little deeper than sexual orientation or skin color.

That said, I am fascinated by the Biological Gender/Androgyny correlations that I often hear people identifying with, on the spectrum.

I enjoyed your "personal" review of that related research done in the last few years, on the website linked below.

http://www.thinkingautismguide.com/search?q=emily+willingham+androgyny

Here is another interesting review of that research from another individual:

http://keithsneuroblog.blogspot.com/2012/08/autism-gender-defiant-disorder.html

Your analogy of the "non-flamboyant" homosexual male mind living in the female body, in one of the links in your article, is reported similarly by some people online per a "non-butch" homosexual female mind living in a male body.

I cannot help but to think that could be an interesting hormonal driven neurodevelopmental difference that in some part is at the core of what makes up online autism communities, as well as many people to date diagnosed with either PDDNOS or Asperger's Syndrome.

There is a popular therapist in my area specializing in Asperger's syndrome. She identifies Androgyny as a common element in her many years of clinical experience.

Androgyny is not one of those things a person can easily mask. It is a neurological and morphological difference following one through the course of a lifetime that often becomes more evident after puberty.

Androgyny can be an issue where self-acceptance is a big part of a solution in potential life-long internal conflicts in differing expressions of two biological genders sharing one body.

I have never particularly identified with a gender, and no longer try to fit a role. That is one advantage of the online experience, which I think is an attractive option for young people to escape that source of potential inner conflict and just be who they are behind an avatar.  

It boggles my mind in trying to figure what the privilege is in having a “gay mind’ and a “straight body”. I do not think that is a "choice" either. It is the farthest thing from typical neurology that I can imagine. :)

However, in all the people I have come across in my lifetime, which is thousands, in working with the public for two decades, those with that type of a-typical neurological/morphological difference, have been some of the most tolerant and accepting of differences in others, that I have come across.

I guess that is part of the "reason'' the gene pool continues to keep them around, as they often accept others for who they are, and can be valued supporting players, even if they do not get around to reproducing. :)

Maybe there is an advantage in having little to no privilege, living center in a much larger spectrum of biological gender difference.

Perhaps it is, most often, the advantage of others or what one might describe as unusual altruism.

Perhaps as far as a type of "Eusocial Primate”.

Maybe just a metaphor or maybe not.

Nevertheless, one not easily forgotten. :)


Additional information associated with Androgyny and 2D/4D Digit Ratio:

http://katiemiaaghogday.blogspot.com/2013/03/aspergers-androgyny-and-2d4d-digit-ratio.html


"Don't Let it Show" by The Alan Parson's Project:

                                                   
http://www.youtube.com/watch?v=0mY-zdEJkNU


Autism, the Internet and "Ideological First Identity", a Collection of Thoughts:

http://katiemiaaghogday.blogspot.com/2013/05/autism-internet-and-ideological-first.html

"AutisticS Peeks!"


It's Good 

to Hear

ya
:)!
*

(:@@
@:)
!*



AS
P:
Autistic Spectrum
Perception

and

Perspective

Update Part 2: Vaccines Not Associated With Autism

5/1/13:

Additional attempts to bridge understanding and knowledge on this overall issue of Vaccines and Autism:

From the Left Brain Right Brain website:

http://leftbrainrightbrain.co.uk/2013/04/30/andrew-wakefield-and-vaccine-safety/


From the Wrong Planet website:

http://www.wrongplanet.net/postt229492.html


From the Thinking Person's Guide to Autism Facebook Page:

https://www.facebook.com/thinkingpersonsguidetoautism/posts/530675340307131


Part two of Update on 4/21/03:

My last and likely final comment quoted below that was not published on the Left Brain Right Brain Website, LBRB, linked below, in the discussion there on the "Vaccine Controversies".

http://leftbrainrightbrain.co.uk/2013/04/17/andrew-wakefield-dont-try-to-blame-me-for-the-results-of-what-i-said-and-did/

It appears that Mr. Carey misunderstood my communication in thinking I was suggesting that Temple Grandin referred to the MMRV, in the NYT interview, when in actuality I was correcting a mistake in communication I had made earlier in the discussion. 

In addition, I provided further information in support of both acknowledgement of the warranted concerns of parents of children who fall ill to severe side effects of vaccines and potential unrelated illness, as well as evidence existing that supports the overall benefit of vaccines vs. the overall cost of potential rare severe side effects

Here is the comment that was not published, to this point in time, with some minor edits for reading clarity:

(4/22/13 Note: Matt Carey from LBRB, did approve this comment and clarified he had problems with the mobile version of his Wordpress Blog. :)

"For clarification and correction regarding my earlier statement in this discussion about the MMRV vaccine, it is approved by the FDA. It is the CDC, not the FDA that does not recommend the MMRV be administered before age four, per recent findings by the Kaiser Vaccine Center.

The CDC's recommendation, as linked below, is for separate vaccinations of MMR and the Varicella vaccine before the age of 48 months (4 yrs.), due to the doubled risk of severe fever and seizures that have been identified in studies of children under the age of two.

The CDC recommends the MMRV vaccine after age four if the MMR vaccine has not been administered separately before age 4.

The risk of severe fever and febrile seizure at age 2 and below is identified as a little over two in 3000, for the MMRV vaccine, as opposed to one in 3000, with the MMR vaccine alone.

Per the 2012 study linked below, from the Kaiser Vaccine Center, the risk drops to 1 in 15,500 at age 4 to 6 for the MMRV vaccine and 1 in 18,000 for the MMR plus Varicella Vaccine.

Temple Grandin may be making her personal risk assessment of recommendation for vaccination at age 5, and what she sees as her own personal list of vulnerabilities associated with ASD, based in part, on this information from the Kaiser Vaccine Center.

However, the danger of not being vaccinated before age 5 based on these numbers alone, which is the newest government reported statistics on risk and side effect of high fevers and febrile seizures associated with MMR and MMRV, definitely does not outweigh the overall risk of what is associated with contracting the actual diseases before age 5 if one is not vaccinated with the MMR or MMRV or MMR plus Varicella Vaccines.

Febrile Seizures alone are not studied as increasing the risk of Epilepsy or Brain damage in the general population.

However, as quoted below from the article that provided further details from the linked abstract, it is worth noting that the peak of the high fevers and febrile seizures occur at 18 months, and typically do not occur after age 5.

The time frame of 18 to 24 months is where the correlation, to date, per regression and timing of event of high fever and illness among children has been identified and reported by parents of a relatively small subgroup of children exhibiting symptoms of developmental regression shortly after these high fevers and/or other elements of illness reported by parents.

This data from the Kaiser Vaccine Center presents a strong case, by itself, of a factor of correlation rather than causation in these vaccine related serious side effects and developmental regression occurring in the same time frame, among a rare sub group of individuals on the spectrum.

http://www.ncbi.nlm.nih.gov/pubmed/22473362

"The researchers noted that febrile seizures typically occur in children ages 6 months to 5 years, and the incidence of these seizures peaks at about 18 months of age."

http://health.usnews.com/health-news/news/articles/2012/04/02/measles-vaccines-wont-raise-seizure-risk-in-young-kids-study

One of the other greatest factors of correlation that may rule out vaccines as an actual direct causal factor per developmental regression is that research has also determined that there is abnormal brain growth specific to males assessed with regressive Autism, which happens well before vaccinations are administered.

This abnormal brain growth is not significantly assessed in a group of females with regressive autism or other children diagnosed on the spectrum at the same age, in that study, linked below:

http://www.ucdmc.ucdavis.edu/publish/news/newsroom/5983

There was a presentation scheduled in the upcoming IMFAR, (International Meeting For Autism Research), in May, on the neuro-pathology of Cavum Septum Pellucidum and Cavum Vergae in Macrocephaly and Autism Spectrum Condition, that could have potentially shed additional light on this issue, but it appears that abstract has been withdrawn and may still be published in the future.

Cavum Septum Pellucidum and Cavum Vergae are already implicated in association in some co-morbid and inter-related genetic based disorders associated with the spectrum such as 22q11 deletion syndrome and Schizophrenia.

https://imfar.confex.com/imfar/2013/webprogram/Paper13947.html

I am a relative "nobody" on the internet, but based on all the evidenced facts that have been presented in this entire discussion, I personally recommend that children should be vaccinated according to CDC recommended vaccination schedule unless a medical doctor advises not to do so based on medical evidence of substantial risk of vulnerability, where the potential cost assessed may be advised as outweighing the potential benefit of vaccination, in rare instances where that determination is made by a qualified physician."


Update on 4/21/13 from my previous blog entry on this issue:

There is a very interesting discussion in the comments section of the Left Brain Right Brain, LBRB website, linked below, in a topic  where Matt Carey went through the historical element of this Vaccine Controversy along with the expression of disgust that exists among some people, associated with Andrew Wakefield and the recent outbreak of Measles in Europe.

There is good information in that discussion for anyone who may be considering Temple Grandin's recent recommendation on her website, in consideration of a delay in MMR vaccination to age 5, if there are familial vulnerabilities that Grandin identifies on her website, in what looks like a quote from her upcoming book, "The Autistic Brain". 

I support what I see as reasonable aspects of her concerns, in the comments section of the discussion linked below; however, in the discussion, I provide the evidence that I am able to locate and link, which still leans heavily toward the benefit of vaccines over the cost of potential rare side effects, even if some of the general vulnerabilities of neurology and health that Grandin identifies, exists per family history. 

My personal opinion that continues as it has been the same in the past, is that only a physician is qualified to determine what type of Health Vulnerability in each unique case is worthy of consideration on a decision whether or not to vaccinate. 

Where there is no health vulnerability assessed by a physician, all the available evidence that exists shows that the benefits of vaccination greatly outweigh the potential costs in risk of side effects that have been studied, identified, and assigned statistical risk in percentage, updated in 2012, as detailed in the discussion, linked below from the LBRB website.

I appreciate Matt Carey, allowing me to participate in the discussion, as a relative Layman on these issues, whereas some of the other individuals discussing the issue appear to have been focused on it for years. 

I do not share the same level of emotional investment that some of the other people in the comments express; however, on the other hand, I am not versed in the level of detail some others have by memory, so it is a research project for me in real time, where I stumble on some of the "vaccine related jargon" that I correct in my comments in the discussion.

In addition, Temple Grandin's website is linked below for those who wish to review the comment that I referenced from her, on that website.

(Edit on 4/28/13:  It appears that all Vaccination related advice has been removed from Temple Grandin's Website linked below)

www.templegrandin.com



http://leftbrainrightbrain.co.uk/2013/04/17/andrew-wakefield-dont-try-to-blame-me-for-the-results-of-what-i-said-and-did/


Original Blog Post from "Vaccines Not Associated With Autism" on 3/30/13:

 
The headline provided by the CDC, in the linked article below, specific to the described study states: "Vaccines not associated with Autism".

Regressive Autism is the only significant subgroup of autism that is the topic of parental observation of concern with vaccines, in the broad autism spectrum and the much broader autism phenotype.

http://www.cdc.gov/vaccinesafety/Concerns/Autism/antigens.html 

This study did not prove there was no association of vaccines with Autism. Specific to the vaccine concern and regressive autism, what it did provide evidence for, as quoted from the article, was this:

"Children with ASD with regression (the loss of developmental skills during the second year of life) did not receive an increased number of vaccine antigens when compared to children without ASD with regression."

This was only an analysis of regressive Autism as defined in the loss of developmental skills during the second year of life, which may have a number of different underlying contributing factors depending on the type of regression.

The regression was not defined specific to loss of language skills, so it is difficult to assess the specific characteristics and severity of the regression, in the sample of 49 children studied. A similar limitation was addressed by Matt Carey, in 2009, in the LBRB blog linked below when an association of Mitochondrial disease, fever, and Regressive Autism was suggested in research. In that study, greater detail was provided in how Regressive Autism was defined than the CDC topic study.
 
http://leftbrainrightbrain.co.uk/2009/09/24/fever-plus-mitochondrial-disease-could-be-risk-factors-for-autistic-regression/
 
Regressive Autism includes a spectrum of specific symptoms and differing severity levels that were defined in the study. There are a number of potential contributing factors for regression.

For one, Hyperlexia is associated with regression in language, and that general condition is estimated in about 5 to 10% of cases of Autism. Another potential contributing factor of risk for regressive Autism is abnormal brain growth associated specific to males with Autistic Disorder.

It is not clear what the direct causal factors are in any of these conditions but there is growing evidence for identified associations that may play a role as contributing factors of risk. What is known about vaccines and identified in the link below, by the CDC, is that there is a risk of fever severe enough to cause seizures in about one out of every 3000 that are vaccinated.

http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-mmr.pdf

There is recent research, as linked below, that seizures, language and motor development in Autism are potentially associated and linked in genetic mutations in duplications of chromosome 15q11-q13, in 1 to 3% of spectrum disorders.

http://www.sciencedaily.com/releases/2013/03/130326101532.htm

One can consider that Autistic Disorder, alone, is currently defined very loosely at this point in time, where 2027 potential combinations of behavioral impairments and/or developmental delays technically could result in a diagnosis where 2 people could be assessed with Autistic Disorder without any intersection of behavioral impairments.

http://crackingtheenigma.blogspot.com/2011/02/exactly-how-many-ways-are-there-to-get.html

It is beyond reason to suggest that one underlying factor could be responsible for Autistic Disorder, considering the complexity of how it is currently defined as a disorder. PDDNOS is currently defined loosely enough by DSMIV standards that a diagnostic tool used to assess PDDNOS in recent research conducted by Catherine Lord and associates, as described in the analysis in the link below, provides a suggestion of a potential misdiagnosis in up to 90% of those assessed in a "non-autistic" group of individuals studied.

http://crackingtheenigma.blogspot.com/2012/10/more-dsm-5-confusion.html

At this point in time, the DSMIV guidelines describe an Autism Spectrum of Disorders that could be associated with almost any factor, including being alive, at least per the diagnostic tool used in Lord's study. It has never been too early to suggest that Vaccines are not the definitive Cause of Autism.

However, it is much too early for the CDC to suggest that there is no association, from this very limited study and the research that has been done to this point. For whatever reason, as provided in research by the CDC, in one out of 3000 people vaccines trigger a side effect of high fevers and seizures. At this point, they do not have clear evidence for why it happens, but it happens.

This is a common issue in many side effects of pharmaceutical intervention. I suspect that if identical research was done in an attempt to disprove that seizures are associated with exposures to greater numbers of antigens from vaccines, that the results would be the same. However, if so, it would be incorrect to suggest that seizures are not associated with Vaccines. They happen. They just don't fully understand why.

It is rare that this happens, but it is also not well understood at all what the actual percentage of children with regressive autism that get severely ill after vaccines are. There is no way to objectively assess that other than a parental survey. However, in rare cases, some children do fall severely ill, and behavioral symptoms of Autism do become more noticeable leading to diagnosis. It happens. They just don't fully understand why.

The underlying factors of seizures cannot always be assessed in an individual. However, the symptoms can be measured by behavior or EEG, when there are no structural anomalies in neurology that can be assessed. There are no clues but behavior in many individuals currently assessed with behavioral impairments associated with ASD's.

At least up until this point, much of the problem in assessing what the causal/contributing factors are is poor diagnostic guidelines that have been used to define what Autism even is, as a neurodevelopmental behaviorally assessed condition.

With DSM5 standards and ICD11beta revision to date, Autism becomes a core behavioral impairment in reciprocal social communication. There is currently no one defined impairment that can be measured by either neurological or behavioral assessment that is core to all Autism Spectrum Disorders, in either DSMIV or ICD10 guidelines, so there can be no potential of one core definitive causal factor. Not even five. Not even 10.

As long as there is the potential of a contributing factor of seizures and potential brain damage, no matter what the underlying factor of the seizures may be, there is the potential of some association. However, at least at this point, per the research that exists, it does not appear to be a potential contributing factor in more than 1 to 3% of the spectrum.

That may not sound like many people but it could comprise 20 to 60K individuals currently estimated as diagnosed, under the loose criteria that exist now. The topic study does not come close to disproving that potential rare association, however small it may be, as a contributing factor.

As a comparative gravity of issue, there were about 7 people that participated in a flash blog that got the attention of a large charitable organization recently, per concern over how the organization describes people on the spectrum in a video about AAC. However, this article, in that same charitable entity's delivery of the research, as communicated here, received much greater amounts of outrage from parents that witnessed their children falling ill after vaccination with observation of greater behavioral impairments after that point. It happens. They don't clearly understand why.

Nevertheless, it understandably, still, is an issue of concern among those that witness this serious issue in their children, in rare cases when it happens. There might not be so much fear of government conspiracies, if the CDC could just state at this point they don't know why this happens as a potential side effect in rare cases after vaccinations. It is reported. It happens.
 
It is much more common than death following a vaccination but potentially less common than one out of 3000 severe fevers and seizures as a side effect of a vaccination. Additional effort at research addressing potential root associations such as genetic mutation, fever, seizures, mitochondrial disease and Autism could still provide additional answers.

However, at this point, a general assessment in a statement of no association by the CDC is not much more believable than a statement of definitive causation. At least, for the limited number of individuals that has witnessed increased observable impairments associated with Autism, happening in their children after vaccination.

It makes it sound like there are many people complaining about it if one limits their world to online resources, but the potential contributing audience, online, is one of global nature and millions of people. It is a similar issue as a couple of hundred people online taking offense at a compassionate portrayal in a video about AAC.

In the real world, it is not on the radar for most people. There are more people listening to the anti-vaccine rhetoric of Alex Jones in the US, than has been attributed to people like Jenny McCarthy. However, in the US, the CDC is doing a great job of promoting what is the overall benefit of vaccines as a lifesaving effort, as the US retains levels close to the highest it has had in the past in "Herd Immunity" in the population at about 95%.

Religious waivers are still the greatest area of refusal to vaccinate other than medical reasons. This is one area, overall, in the US, per society adherence to the medical model of disability, in advantage in keeping the population healthy. The US was hardly phased by the Wakefield Vaccine/Autism research, whereas in Europe there was a substantial causal effect associated lowering the assessed vaccination rates below "herd immunity" in 80-percentile territory.



For anyone that made it this far, in this compiling of data, in three of my blog posts here is an additional avenue of potential interest. :)


The Autism Research Scientist that writes in the Blog linked below provides a virtual "Goldmine" of resources addressing the Co-morbid conditions associated with what is currently described and defined as the Autism Spectrum under DSMIV guidelines.

In regard to GI issues and Autism, and all the research that is coming out now, that is farther removed from the "vaccine controversies", this Autism Research Scientist's post linked here and the comments on it, provide an excellent overview of the state of science on this issue of GI difficulties and Autism, leaving the "vaccine controversies" in the dust, so to speak.

All of the blogs he lists on his blogroll are worth taking a look at when one who is interested in this kind of science, has the time.

http://questioning-answers.blogspot.co.uk/2013/03/gastrointestinal-mucosal-molecular-profile-autism.html




Autism, the Internet and "Ideological First Identity", a Collection of Thoughts:

http://katiemiaaghogday.blogspot.com/2013/05/autism-internet-and-ideological-first.html

"AutisticS Peeks!"


It's Good

to Hear

ya
:)!
*

(:@@
@:)
!*


AS
P:
Autistic Spectrum
Perception

and

Perspective

Update: "Vaccines Not Associated With Autism"

Update on 4/21/13:

There is a very interesting discussion in the comments section of the Left Brain Right Brain, LBRB website, linked below, in a topic  where Matt Carey went through the historical element of this Vaccine Controversy along with the expression of disgust that exists among some people, associated with Andrew Wakefield and the recent outbreak of Measles in Europe.

There is good information in that discussion for anyone who may be considering Temple Grandin's recent recommendation on her website, in consideration of a delay in MMR vaccination to age 5, if there are familial vulnerabilities that Grandin identifies on her website, in what looks like a quote from her upcoming book, "The Autistic Brain". 

I support what I see as reasonable aspects of her concerns, in the comments section of the discussion linked below; however, in the discussion, I provide the evidence that I am able to locate and link, which still leans heavily toward the benefit of vaccines over the cost of potential rare side effects, even if some of the general vulnerabilities of neurology and health that Grandin identifies, exists per family history. 

My personal opinion that continues as it has been the same in the past, is that only a physician is qualified to determine what type of Health Vulnerability in each unique case is worthy of consideration on a decision whether or not to vaccinate. 

Where there is no health vulnerability assessed by a physician, all the available evidence that exists shows that the benefits of vaccination greatly outweigh the potential costs in risk of side effects that have been studied, identified, and assigned statistical risk in percentage, updated in 2012, as detailed in the discussion, linked below from the LBRB website.

I appreciate Matt Carey, allowing me to participate in the discussion, as a relative Layman on these issues, whereas some of the other individuals discussing the issue appear to have been focused on it for years. 

I do not share the same level of emotional investment that some of the other people in the comments express; however, on the other hand, I am not versed in the level of detail some others have by memory, so it is a research project for me in real time, where I stumble on some of the "vaccine related jargon" that I correct in my comments in the discussion.

In addition, Temple Grandin's website is linked below for those who wish to review the comment that I referenced from her, on that website.

www.templegrandin.com



http://leftbrainrightbrain.co.uk/2013/04/17/andrew-wakefield-dont-try-to-blame-me-for-the-results-of-what-i-said-and-did/

Original Blog Post from "Vaccines Not Associated With Autism" on 3/30/13:

 
The headline provided by the CDC, in the linked article below, specific to the described study states: "Vaccines not associated with Autism".

Regressive Autism is the only significant subgroup of autism that is the topic of parental observation of concern with vaccines, in the broad autism spectrum and the much broader autism phenotype.

http://www.cdc.gov/vaccinesafety/Concerns/Autism/antigens.html 

This study did not prove there was no association of vaccines with Autism. Specific to the vaccine concern and regressive autism, what it did provide evidence for, as quoted from the article, was this:

"Children with ASD with regression (the loss of developmental skills during the second year of life) did not receive an increased number of vaccine antigens when compared to children without ASD with regression."

This was only an analysis of regressive Autism as defined in the loss of developmental skills during the second year of life, which may have a number of different underlying contributing factors depending on the type of regression.

The regression was not defined specific to loss of language skills, so it is difficult to assess the specific characteristics and severity of the regression, in the sample of 49 children studied. A similar limitation was addressed by Matt Carey, in 2009, in the LBRB blog linked below when an association of Mitochondrial disease, fever, and Regressive Autism was suggested in research. In that study, greater detail was provided in how Regressive Autism was defined than the CDC topic study.
 
http://leftbrainrightbrain.co.uk/2009/09/24/fever-plus-mitochondrial-disease-could-be-risk-factors-for-autistic-regression/
 
Regressive Autism includes a spectrum of specific symptoms and differing severity levels that were defined in the study. There are a number of potential contributing factors for regression.

For one, Hyperlexia is associated with regression in language, and that general condition is estimated in about 5 to 10% of cases of Autism. Another potential contributing factor of risk for regressive Autism is abnormal brain growth associated specific to males with Autistic Disorder.

It is not clear what the direct causal factors are in any of these conditions but there is growing evidence for identified associations that may play a role as contributing factors of risk. What is known about vaccines and identified in the link below, by the CDC, is that there is a risk of fever severe enough to cause seizures in about one out of every 3000 that are vaccinated.

http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-mmr.pdf

There is recent research, as linked below, that seizures, language and motor development in Autism are potentially associated and linked in genetic mutations in duplications of chromosome 15q11-q13, in 1 to 3% of spectrum disorders.

http://www.sciencedaily.com/releases/2013/03/130326101532.htm

One can consider that Autistic Disorder, alone, is currently defined very loosely at this point in time, where 2027 potential combinations of behavioral impairments and/or developmental delays technically could result in a diagnosis where 2 people could be assessed with Autistic Disorder without any intersection of behavioral impairments.

http://crackingtheenigma.blogspot.com/2011/02/exactly-how-many-ways-are-there-to-get.html

It is beyond reason to suggest that one underlying factor could be responsible for Autistic Disorder, considering the complexity of how it is currently defined as a disorder. PDDNOS is currently defined loosely enough by DSMIV standards that a diagnostic tool used to assess PDDNOS in recent research conducted by Catherine Lord and associates, as described in the analysis in the link below, provides a suggestion of a potential misdiagnosis in up to 90% of those assessed in a "non-autistic" group of individuals studied.

http://crackingtheenigma.blogspot.com/2012/10/more-dsm-5-confusion.html

At this point in time, the DSMIV guidelines describe an Autism Spectrum of Disorders that could be associated with almost any factor, including being alive, at least per the diagnostic tool used in Lord's study. It has never been too early to suggest that Vaccines are not the definitive Cause of Autism.

However, it is much too early for the CDC to suggest that there is no association, from this very limited study and the research that has been done to this point. For whatever reason, as provided in research by the CDC, in one out of 3000 people vaccines trigger a side effect of high fevers and seizures. At this point, they do not have clear evidence for why it happens, but it happens.

This is a common issue in many side effects of pharmaceutical intervention. I suspect that if identical research was done in an attempt to disprove that seizures are associated with exposures to greater numbers of antigens from vaccines, that the results would be the same. However, if so, it would be incorrect to suggest that seizures are not associated with Vaccines. They happen. They just don't fully understand why.

It is rare that this happens, but it is also not well understood at all what the actual percentage of children with regressive autism that get severely ill after vaccines are. There is no way to objectively assess that other than a parental survey. However, in rare cases, some children do fall severely ill, and behavioral symptoms of Autism do become more noticeable leading to diagnosis. It happens. They just don't fully understand why.

The underlying factors of seizures cannot always be assessed in an individual. However, the symptoms can be measured by behavior or EEG, when there are no structural anomalies in neurology that can be assessed. There are no clues but behavior in many individuals currently assessed with behavioral impairments associated with ASD's.

At least up until this point, much of the problem in assessing what the causal/contributing factors are is poor diagnostic guidelines that have been used to define what Autism even is, as a neurodevelopmental behaviorally assessed condition.

With DSM5 standards and ICD11beta revision to date, Autism becomes a core behavioral impairment in reciprocal social communication. There is currently no one defined impairment that can be measured by either neurological or behavioral assessment that is core to all Autism Spectrum Disorders, in either DSMIV or ICD10 guidelines, so there can be no potential of one core definitive causal factor. Not even five. Not even 10.

As long as there is the potential of a contributing factor of seizures and potential brain damage, no matter what the underlying factor of the seizures may be, there is the potential of some association. However, at least at this point, per the research that exists, it does not appear to be a potential contributing factor in more than 1 to 3% of the spectrum.

That may not sound like many people but it could comprise 20 to 60K individuals currently estimated as diagnosed, under the loose criteria that exist now. The topic study does not come close to disproving that potential rare association, however small it may be, as a contributing factor.

As a comparative gravity of issue, there were about 7 people that participated in a flash blog that got the attention of a large charitable organization recently, per concern over how the organization describes people on the spectrum in a video about AAC. However, this article, in that same charitable entity's delivery of the research, as communicated here, received much greater amounts of outrage from parents that witnessed their children falling ill after vaccination with observation of greater behavioral impairments after that point. It happens. They don't clearly understand why.

Nevertheless, it understandably, still, is an issue of concern among those that witness this serious issue in their children, in rare cases when it happens. There might not be so much fear of government conspiracies, if the CDC could just state at this point they don't know why this happens as a potential side effect in rare cases after vaccinations. It is reported. It happens.
 
It is much more common than death following a vaccination but potentially less common than one out of 3000 severe fevers and seizures as a side effect of a vaccination. Additional effort at research addressing potential root associations such as genetic mutation, fever, seizures, mitochondrial disease and Autism could still provide additional answers.

However, at this point, a general assessment in a statement of no association by the CDC is not much more believable than a statement of definitive causation. At least, for the limited number of individuals that has witnessed increased observable impairments associated with Autism, happening in their children after vaccination.

It makes it sound like there are many people complaining about it if one limits their world to online resources, but the potential contributing audience, online, is one of global nature and millions of people. It is a similar issue as a couple of hundred people online taking offense at a compassionate portrayal in a video about AAC.

In the real world, it is not on the radar for most people. There are more people listening to the anti-vaccine rhetoric of Alex Jones in the US, than has been attributed to people like Jenny McCarthy. However, in the US, the CDC is doing a great job of promoting what is the overall benefit of vaccines as a lifesaving effort, as the US retains levels close to the highest it has had in the past in "Herd Immunity" in the population at about 95%.

Religious waivers are still the greatest area of refusal to vaccinate other than medical reasons. This is one area, overall, in the US, per society adherence to the medical model of disability, in advantage in keeping the population healthy. The US was hardly phased by the Wakefield Vaccine/Autism research, whereas in Europe there was a substantial causal effect associated lowering the assessed vaccination rates below "herd immunity" in 80-percentile territory.

For anyone that made it this far, in this compiling of data, in two of my blog posts here is an additional avenue of potential interest. :)


The Autism Research Scientist that writes in the Blog linked below provides a virtual "Goldmine" of resources addressing the Co-morbid conditions associated with what is currently described and defined as the Autism Spectrum under DSMIV guidelines.

In regard to GI issues and Autism, and all the research that is coming out now, that is farther removed from the "vaccine controversies", this Autism Research Scientist's post linked here and the comments on it, provide an excellent overview of the state of science on this issue of GI difficulties and Autism, leaving the "vaccine controversies" in the dust, so to speak.

All of the blogs he lists on his blogroll are worth taking a look at when one who is interested in this kind of science, has the time.

http://questioning-answers.blogspot.co.uk/2013/03/gastrointestinal-mucosal-molecular-profile-autism.html



Autism, the Internet and "Ideological First Identity", a Collection of Thoughts:

http://katiemiaaghogday.blogspot.com/2013/05/autism-internet-and-ideological-first.html

"AutisticS Peeks!"


It's Good

to Hear

ya
:)!
*

(:@@
@:)
!*



AS
P:
Autistic Spectrum
Perception

and

Perspective

Continuing Controversies over "I want to Say" and "Autism Speaks"

More about the Autism Speaks "I want to Say" Video linked below and the ongoing "Autism Speaks Controversies" in the Autism Community:

[name redacted], I visited your "ASD page" two times to post, since the last time you deleted my comment. One visit was in support of your opinion on the Basketball Game issue and the other was to support your opinion on Marriage Equality.

I posted on your page this time to offer support to another human being that I thought had a reasonable point of view. I also was defending the young man's love and mother's love for the young man in the video, by clarifying a statement that was taken out of context.

Several people have taken what the mother said about she and her husband "TELLING THEIR SON TOGETHER that he is sweet for an autistic child" out of context.

In effect, what that has done has made a message of acceptance into a message of hatred for her son. It could have reasonably been offensive if the message had been addressed at someone other than her son, but it wasn't.

The reason some people took it out of context is because they were not fully listening or could not understand what the mother said in the video.

It is unlikely you took the time or effort to read my reasonable comment below. It was likely more efficient for you to silence an autistic person over unwarranted offense against the organization, this go around.

That is a problem with anger and hatred towards others; it often ends up hurting others, unintentionally. No one sharing this empathy of anger appears to be thinking about the young man's love for his mother and how he would feel if he read about people treating his mother this way.
 
Nor do they seem to be considering the way the two actual autistic people speaking with the AAC technology might feel if they heard the comments on the Autism Speaks website blog minimizing their efforts in the video, as part of an overall harmful effort.

Autistic people were talking in the video but some were not taking the time to listen...

It is the reason I commented in the first place on your page, months ago, defending Erin Clemens as an autistic individual where I took the time and effort to listen to what she was saying...

Not many others were listening.
 
The reason for that seems clear: Anger and Hatred...
 
You do not silence me; you make my voice louder. However, you are silencing other Autistic people with this unwarranted hatred and anger, whether it is intentional or not.

Here is my comment again, below, if you care to read it. Many others will have that opportunity on the Autism Speaks Blog addressing the issue. You helped to make that possible by motivating my comment.

I can only thank you for that. :)

You can still do that for me in the future, whether or not you allow me to comment on your page or not. I suspect that you will. :)

"It was encouraging to see at least one person in the flash blog, linked below, that assessed the video, the voices of the children who spoke through AAC technology, and autism speaks effort as an overall positive one.

http://thautcast.com/drupal5/content/autism-speaks-progress-report

At least one other person had the civility to state that the film was not all bad. I think that is what the representative of Autism Speaks was valuing in the statement of appreciation, linked below along with the topic video, that people did take the time and effort to offer a variety of perspectives, instead of a common message of contempt.
 
http://www.autismspeaks.org/blog/2013/03/28/about-i-want-say



http://www.youtube.com/watch?v=Iu3c8fqBQcA

 
I do not think a statement like that would have been made by the organization if that civil effort had not been made in any of the blog posts. It would be like throwing salt in a wound and may still feel like that for those that only expressed contempt.

Perhaps the voices of one young man in grade school and one young adult woman in college, providing personal insight through the AAC technology, was not impressive enough for some, but it was impressive to me.

I am usually impressed by the insights provided by Temple Grandin and always welcome them. Her voice is not getting old to me.

These voices likely would not have been heard as an inspirational one to thousands of others, without this effort of the organization, those individuals on the spectrum who provided their voices through the technology, and those who worked to accomplish that goal together. It is a team effort, not a solitary one.

Those voices can become even louder in the future, if they are not silenced by others over differences in opinion over organizational missions, and instead amplifying the positive voices and sentiments on and off the spectrum that are being expressed in efforts like this.

I give the blogger linked above credit for providing a fair and balanced approach to this overall division in the autism community that remains for some.

The amount of criticism over the mother of the child on the spectrum stating: "we tell our son together he is really sweet for being an autistic child", was over a statement that was not likely a literal statement of a full quote delivered to her son.

Not all children with Autism are overly affectionate. I don't think it was a requirement to amplify that reality in the video, in setting the son apart from others on the spectrum, but the mother and the father are obviously proud of their son and only encouraging the positive qualities of their son by complimenting him as being a sweet boy, regardless if he is autistic or not.

That was not a personal message worth censoring to me, in my opinion.
 
There was love, compassion, challenge, sobriety of difficulties that not all share on the spectrum, along with passion expressed to help the children and young adults in the video.

There were also many different perspectives offered. There was little to no emotion of pity expressed in this film, instead, almost entirely a positive message for the future of all of these children.

Perhaps I can see that better than some because I have not watched the previous two videos that some took offense to years ago that portrayed heart-breaking sentiment, ten or fifteen times in contempt for the organization.

That can bring preconceived emotional perceptions to an analysis of this much more positive effort of message to society about the future of people on the spectrum, with or without what is often described by some as a 'cure'."

Autism, the Internet and "Ideological First Identity", a Collection of Thoughts:

http://katiemiaaghogday.blogspot.com/2013/05/autism-internet-and-ideological-first.html

"AutisticS Peeks!"


It's Good

to Hear

ya
:)!
*

(:@@
@:)
!*


AS
P:
Autistic Spectrum
Perception

and

Perspective

"Vaccines not Associated with Autism"

The headline provided by the CDC, in the linked article below specific to the described study states: "Vaccines not associated with Autism".

Regressive Autism is the only significant subgroup of autism that is the topic of parental observation of concern with vaccines, in the broad autism spectrum and the much broader autism phenotype.

http://www.cdc.gov/vaccinesafety/Concerns/Autism/antigens.html 

This study did not prove there was no association of vaccines with Autism. Specific to the vaccine concern and regressive autism, what it did provide evidence for, as quoted from the article, was this:

"Children with ASD with regression (the loss of developmental skills during the second year of life) did not receive an increased number of vaccine antigens when compared to children without ASD with regression."

This was only an analysis of regressive Autism as defined in the loss of developmental skills during the second year of life, which may have a number of different underlying contributing factors depending on the type of regression.

The regression was not defined specific to loss of language skills, so it is difficult to assess the specific characteristics and severity of the regression, in the sample of 49 children studied. A similar limitation was addressed by Matt Carey, in 2009, in the LBRB blog linked below when an association of Mitochondrial disease, fever, and Regressive Autism was suggested in research. In that study, greater detail was provided in how Regressive Autism was defined than the CDC topic study.
 
http://leftbrainrightbrain.co.uk/2009/09/24/fever-plus-mitochondrial-disease-could-be-risk-factors-for-autistic-regression/
 
Regressive Autism includes a spectrum of specific symptoms and differing severity levels that were defined in the study. There are a number of potential contributing factors for regression.

For one, Hyperlexia is associated with regression in language, and that general condition is estimated in about 5 to 10% of cases of Autism. Another potential contributing factor of risk for regressive Autism is abnormal brain growth associated specific to males with Autistic Disorder.

It is not clear what the direct causal factors are in any of these conditions but there is growing evidence for identified associations that may play a role as contributing factors of risk. What is known about vaccines and identified in the link below, by the CDC, is that there is a risk of fever severe enough to cause seizures in about one out of every 3000 that are vaccinated.

http://www.cdc.gov/vaccines/pubs/vis/downloads/vis-mmr.pdf

There is recent research, as linked below, that seizures, language and motor development in Autism are potentially associated and linked in genetic mutations in duplications of chromosome 15q11-q13, in 1 to 3% of spectrum disorders.

http://www.sciencedaily.com/releases/2013/03/130326101532.htm

One can consider that Autistic Disorder, alone, is currently defined very loosely at this point in time, where 2027 potential combinations of behavioral impairments and/or developmental delays technically could result in a diagnosis where 2 people could be assessed with Autistic Disorder without any intersection of behavioral impairments.

http://crackingtheenigma.blogspot.com/2011/02/exactly-how-many-ways-are-there-to-get.html

It is beyond reason to suggest that one underlying factor could be responsible for Autistic Disorder, considering the complexity of how it is currently defined as a disorder. PDDNOS is currently defined loosely enough by DSMIV standards that a diagnostic tool used to assess PDDNOS in recent research conducted by Catherine Lord and associates, as described in the analysis in the link below, provides a suggestion of a potential misdiagnosis in up to 90% of those assessed in a "non-autistic" group of individuals studied.

http://crackingtheenigma.blogspot.com/2012/10/more-dsm-5-confusion.html

At this point in time, the DSMIV guidelines describe an Autism Spectrum of Disorders that could be associated with almost any factor, including being alive, at least per the diagnostic tool used in Lord's study. It has never been too early to suggest that Vaccines are not the definitive Cause of Autism.

However, it is much too early for the CDC to suggest that there is no association, from this very limited study and the research that has been done to this point. For whatever reason, as provided in research by the CDC, in one out of 3000 people vaccines trigger a side effect of high fevers and seizures. At this point, they do not have clear evidence for why it happens, but it happens.

This is a common issue in many side effects of pharmaceutical intervention. I suspect that if identical research was done in an attempt to disprove that seizures are associated with exposures to greater numbers of antigens from vaccines, that the results would be the same. However, if so, it would be incorrect to suggest that seizures are not associated with Vaccines. They happen. They just don't fully understand why.

It is rare that this happens, but it is also not well understood at all what the actual percentage of children with regressive autism that get severely ill after vaccines are. There is no way to objectively assess that other than a parental survey. However, in rare cases, some children do fall severely ill, and behavioral symptoms of Autism do become more noticeable leading to diagnosis. It happens. They just don't fully understand why.

The underlying factors of seizures cannot always be assessed in an individual. However, the symptoms can be measured by behavior or EEG, when there are no structural anomalies in neurology that can be assessed. There are no clues but behavior in many individuals currently assessed with behavioral impairments associated with ASD's.

At least up until this point, much of the problem in assessing what the causal/contributing factors are is poor diagnostic guidelines that have been used to define what Autism even is, as a neurodevelopmental behaviorally assessed condition.

With DSM5 standards and ICD11beta revision to date, Autism becomes a core behavioral impairment in reciprocal social communication. There is currently no one defined impairment that can be measured by either neurological or behavioral assessment that is core to all Autism Spectrum Disorders, in either DSMIV or ICD10 guidelines, so there can be no potential of one core definitive causal factor. Not even five. Not even 10.

As long as there is the potential of a contributing factor of seizures and potential brain damage, no matter what the underlying factor of the seizures may be, there is the potential of some association. However, at least at this point, per the research that exists, it does not appear to be a potential contributing factor in more than 1 to 3% of the spectrum.

That may not sound like many people but it could comprise 20 to 60K individuals currently estimated as diagnosed, under the loose criteria that exist now. The topic study does not come close to disproving that potential rare association, however small it may be, as a contributing factor.

As a comparative gravity of issue, there were about 7 people that participated in a flash blog that got the attention of a large charitable organization recently, per concern over how the organization describes people on the spectrum in a video about AAC. However, this article, in that same charitable entity's delivery of the research, as communicated here, received much greater amounts of outrage from parents that witnessed their children falling ill after vaccination with observation of greater behavioral impairments after that point. It happens. They don't clearly understand why.

Nevertheless, it understandably, still, is an issue of concern among those that witness this serious issue in their children, in rare cases when it happens. There might not be so much fear of government conspiracies, if the CDC could just state at this point they don't know why this happens as a potential side effect in rare cases after vaccinations. It is reported. It happens.
 
It is much more common than death following a vaccination but potentially less common than one out of 3000 severe fevers and seizures as a side effect of a vaccination. Additional effort at research addressing potential root associations such as genetic mutation, fever, seizures, mitochondrial disease and Autism could still provide additional answers.

However, at this point, a general assessment in a statement of no association by the CDC is not much more believable than a statement of definitive causation. At least, for the limited number of individuals that has witnessed increased observable impairments associated with Autism, happening in their children after vaccination.

It makes it sound like there are many people complaining about it if one limits their world to online resources, but the potential contributing audience, online, is one of global nature and millions of people. It is a similar issue as a couple of hundred people online taking offense at a compassionate portrayal in a video about AAC.

In the real world, it is not on the radar for most people. There are more people listening to the anti-vaccine rhetoric of Alex Jones in the US, than has been attributed to people like Jenny McCarthy. However, in the US, the CDC is doing a great job of promoting what is the overall benefit of vaccines as a lifesaving effort, as the US retains levels close to the highest it has had in the past in "Herd Immunity" in the population at about 95%.

Religious waivers are still the greatest area of refusal to vaccinate other than medical reasons. This is one area, overall, in the US, per society adherence to the medical model of disability, in advantage in keeping the population healthy. The US was hardly phased by the Wakefield Vaccine/Autism research, whereas in Europe there was a substantial causal effect associated lowering the assessed vaccination rates below "herd immunity" in 80-percentile territory.


Update on 4/21/13:

There is a very interesting discussion in the comments section of the Left Brain Right Brain, LBRB website, linked below, in a topic  where Matt Carey went through the historical element of this Vaccine Controversy along with the expression of disgust that exists among some people, associated with Andrew Wakefield and the recent outbreak of Measles in Europe.

There is good information in that discussion for anyone who may be considering Temple Grandin's recent recommendation on her website, in consideration of a delay in MMR vaccination to age 5, if there are familial vulnerabilities that Grandin identifies on her website, in what looks like a quote from her upcoming book, "The Autistic Brain". 

I support what I see as reasonable aspects of her concerns, in the comments section of the discussion linked below; however, in the discussion, I provide the evidence that I am able to locate and link, which still leans heavily toward the benefit of vaccines over the cost of potential rare side effects, even if some of the general vulnerabilities of neurology and health that Grandin identifies, exists per family history. 

My personal opinion that continues as it has been the same in the past, is that only a physician is qualified to determine what type of Health Vulnerability in each unique case is worthy of consideration on a decision whether or not to vaccinate. 

Where there is no health vulnerability assessed by a physician, all the available evidence that exists shows that the benefits of vaccination greatly outweigh the potential costs in risk of side effects that have been studied, identified, and assigned statistical risk in percentage, updated in 2012, as detailed in the discussion, linked below from the LBRB website.

I appreciate Matt Carey, allowing me to participate in the discussion, as a relative Layman on these issues, whereas some of the other individuals discussing the issue appear to have been focused on it for years. 

I do not share the same level of emotional investment that some of the other people in the comments express; however, on the other hand, I am not versed in the level of detail some others have by memory, so it is a research project for me in real time, where I stumble on some of the "vaccine related jargon" that I correct in my comments in the discussion.

In addition, Temple Grandin's website is linked below for those who wish to review the comment that I referenced from her, on that website.


(Edit on 4/28/13:  It appears that all Vaccination related advice has been removed from Temple Grandin's Website linked below)


www.templegrandin.com



http://leftbrainrightbrain.co.uk/2013/04/17/andrew-wakefield-dont-try-to-blame-me-for-the-results-of-what-i-said-and-did/  


Part two of Update on 4/21/03:

My last and likely final comment quoted below that was not published on the Left Brain Right Brain Website, LBRB, linked below, in the discussion there on the "Vaccine Controversies".

http://leftbrainrightbrain.co.uk/2013/04/17/andrew-wakefield-dont-try-to-blame-me-for-the-results-of-what-i-said-and-did/

It appears that Mr. Carey misunderstood my communication in thinking I was suggesting that Temple Grandin referred to the MMRV, in the NYT interview, when in actuality I was correcting a mistake in communication I had made earlier in the discussion. 

In addition, I provided further information in support of both acknowledgement of the warranted concerns of parents of children who fall ill to severe side effects of vaccines and potential unrelated illness, as well as evidence existing that supports the overall benefit of vaccines vs. the overall cost of potential rare severe side effects.

Here is the comment that was not published, to this point in time, with some minor edits for reading clarity:

(Note: Matt Carey from LBRB, did approve my last comment and clarified he had problems with the mobile version of his Wordpress Blog. :)

"For clarification and correction regarding my earlier statement in this discussion about the MMRV vaccine, it is approved by the FDA. It is the CDC, not the FDA that does not recommend the MMRV be administered before age four, per recent findings by the Kaiser Vaccine Center.

The CDC's recommendation, as linked below, is for separate vaccinations of MMR and the Varicella vaccine before the age of 48 months (4 yrs.), due to the doubled risk of severe fever and seizures that have been identified in studies of children under the age of two.

The CDC recommends the MMRV vaccine after age four if the MMR vaccine has not been administered separately before age 4.

The risk of severe fever and febrile seizure at age 2 and below is identified as a little over two in 3000, for the MMRV vaccine, as opposed to one in 3000, with the MMR vaccine alone.

Per the 2012 study linked below, from the Kaiser Vaccine Center, the risk drops to 1 in 15,500 at age 4 to 6 for the MMRV vaccine and 1 in 18,000 for the MMR plus Varicella Vaccine.

Temple Grandin may be making her personal risk assessment of recommendation for vaccination at age 5, and what she sees as her own personal list of vulnerabilities associated with ASD, based in part, on this information from the Kaiser Vaccine Center.

However, the danger of not being vaccinated before age 5 based on these numbers alone, which is the newest government reported statistics on risk and side effect of high fevers and febrile seizures associated with MMR and MMRV, definitely does not outweigh the overall risk of what is associated with contracting the actual diseases before age 5 if one is not vaccinated with the MMR or MMRV or MMR plus Varicella Vaccines.

Febrile Seizures alone are not studied as increasing the risk of Epilepsy or Brain damage in the general population.

However, as quoted below from the article that provided further details from the linked abstract, it is worth noting that the peak of the high fevers and febrile seizures occur at 18 months, and typically do not occur after age 5.

The time frame of 18 to 24 months is where the correlation, to date, per regression and timing of event of high fever and illness among children has been identified and reported by parents of a relatively small subgroup of children exhibiting symptoms of developmental regression shortly after these high fevers and/or other elements of illness reported by parents.

This data from the Kaiser Vaccine Center presents a strong case, by itself, of a factor of correlation rather than causation in these vaccine related serious side effects and developmental regression occurring in the same time frame, among a rare sub group of individuals on the spectrum.

http://www.ncbi.nlm.nih.gov/pubmed/22473362

"The researchers noted that febrile seizures typically occur in children ages 6 months to 5 years, and the incidence of these seizures peaks at about 18 months of age."

http://health.usnews.com/health-news/news/articles/2012/04/02/measles-vaccines-wont-raise-seizure-risk-in-young-kids-study

One of the other greatest factors of correlation that may rule out vaccines as an actual direct causal factor per developmental regression is that research has also determined that there is abnormal brain growth specific to males assessed with regressive Autism, which happens well before vaccinations are administered.This abnormal brain growth is not significantly assessed in a group of females with regressive autism or other children diagnosed on the spectrum at the same age, in that study, linked below:

http://www.ucdmc.ucdavis.edu/publish/news/newsroom/5983

There was a presentation scheduled in the upcoming IMFAR, (International Meeting For Autism Research), in May, on the neuro-pathology of Cavum Septum Pellucidum and Cavum Vergae in Macrocephaly and Autism Spectrum Condition, that could have potentially shed additional light on this issue, but it appears that abstract has been withdrawn and may still be published in the future.

Cavum Septum Pellucidum and Cavum Vergae are already implicated in association in some co-morbid and inter-related genetic based disorders associated with the spectrum such as 22q11 deletion syndrome and Schizophrenia.

https://imfar.confex.com/imfar/2013/webprogram/Paper13947.html

I am a relative "nobody" on the internet, but based on all the evidenced facts that have been presented in this entire discussion, I personally recommend that children should be vaccinated according to CDC recommended vaccination schedule unless a medical doctor advises not to do so based on medical evidence of substantial risk of vulnerability, where the potential cost assessed may be advised as outweighing the potential benefit of vaccination, in rare instances where that determination is made by a qualified physician."


For anyone that made it this far, in this compiling of data, in three of my blog posts here is an additional avenue of potential interest. :)


The Autism Research Scientist that writes in the Blog linked below provides a virtual "Goldmine" of resources addressing the Co-morbid conditions associated with what is currently described and defined as the Autism Spectrum under DSMIV guidelines.

In regard to GI issues and Autism, and all the research that is coming out now, that is farther removed from the "vaccine controversies", this Autism Research Scientist's post linked here and the comments on it, provide an excellent overview of the state of science on this issue of GI difficulties and Autism, leaving the "vaccine controversies" in the dust, so to speak.

All of the blogs he lists on his blogroll are worth taking a look at when one who is interested in this kind of science, has the time.

http://questioning-answers.blogspot.co.uk/2013/03/gastrointestinal-mucosal-molecular-profile-autism.html


5/1/13:

Additional attempts to bridge understanding and knowledge on this overall issue of Vaccines and Autism:
From the Left Brain Right Brain website:

http://leftbrainrightbrain.co.uk/2013/04/30/andrew-wakefield-and-vaccine-safety/


From the Wrong Planet website:

http://www.wrongplanet.net/postt229492.html


From the Thinking Person's Guide to Autism Facebook Page:

https://www.facebook.com/thinkingpersonsguidetoautism/posts/530675340307131

Autism, the Internet and "Ideological First Identity", a Collection of Thoughts:

http://katiemiaaghogday.blogspot.com/2013/05/autism-internet-and-ideological-first.html

"AutisticS Peeks!"


It's Good

to Hear

ya
:)!
*

(:@@
@:)
!*



AS
P:
Autistic Spectrum
Perception

and

Perspective